Publications

NK-A 17E-233I: a novel competitive inhibitor of human dihydroorotate dehydrogenase (DHODH) for cancer therapy. Anwar M.M., Meseguer S., García-Rodríguez N., Krupinska E., Sele C., Rodríguez-Jiménez A., Verma S., Sagadevan S., Ramon J., Martí R., Occhipinti A., Angione C., Ordóñez-Morán P., Knecht W., Huertas P., Juanes M.A. DOI: 10.1186/s13046-025-03538-w

The roles of yeast formins and their regulators Bud6 and Bil2 in the pheromone response. Magliozzi J.O., Rands T.J., Shrestha S., Simke W.C., Hase N.E., Juanes M.A., Kelley J.B., Goode B.L. Molecular Biology of the Cell. DOI: 10.1091/mbc.E23-11-0459

Tumor invasiveness is regulated by the concerted function of APC, formins, and Arp2/3 complex. Baro L., Almhassneh R.A., Islam A., Juanes M.A. iScience. DOI: 10.1016/j.isci.2024.109687

Confocal Laser Scanning Imaging of Cell Junctions in Human Colon Cancer Cells. Zhou P., Juanes M.A. Book chapter in: Ordóñez-Morán P. (eds) Intestinal Differentiated Cells, Methods in Molecular Biology, vol. 2650. Humana, New York, NY. DOI: 10.1007/978-1-0716-3076-1_19

Automated Quantitative Analysis of Shape Features in Human Epithelial Monolayers and Spheroids Generated from Colorectal Cancer Cells. Brown H.M., Juanes M.A. Book chapter in: Ordóñez-Morán P. (eds) Intestinal Differentiated Cells, Methods in Molecular Biology, vol. 2650. Humana, New York, NY. DOI: 10.1007/978-1-0716-3076-1_20

APC-driven actin nucleation controls collective cell remodeling and motility in colorectal cancer cells. Baro L.#, Islam A.#, Brown H.M., Bell Z.A., Juanes M.A.* (#equal contribution, *corresponding author). iScience, Elsevier. DOI: 10.1016/j.isci.2023.106583

The compass to follow: Focal adhesion turnover. Mavrakis M., Juanes M.A.* (*corresponding author). Current Opinion in Cell Biology. DOI: 10.1016/j.ceb.2023.102152

Cytoskeletal control and Wnt Signaling — APC’s Dual Contributions in Stem Cell Division and Colorectal Cancer. Juanes M.A.* (*corresponding author). Cancers, MDPI. DOI: 10.3390/cancers12123811

EB1 directly regulates APC-mediated actin nucleation. Juanes M.A.*, Fees C.P., Hoeprich G.J., Jaiswal R., Goode B.L.* (*co-corresponding authors). Current Biology, 30(23), pp. 4763–4772. DOI: 10.1016/j.cub.2020.08.094

The role of APC-mediated actin assembly in microtubule capture and focal adhesion turnover. Juanes M.A.*, Isnardon D., Badache A., Brasselet S., Mavrakis M., Goode B.L.* (*co-corresponding authors). Journal of Cell Biology, 218(10), pp. 3415–3435. DOI: 10.1083/jcb.201904165

Recruitment of the mitotic exit network to yeast centrosomes couples septin displacement to actomyosin constriction. Tamborrini D., Juanes M.A., Ibanes S., Rancati G., Piatti S. Nature Communications. DOI: 10.1038/s41467-018-06767-0

Profilin Directly Promotes Microtubule Growth through Residues Mutated in Amyotrophic Lateral Sclerosis. Henty-Ridilla J.L., Juanes M.A., Goode B.L. Current Biology, 27(22), pp. 3535–3543. DOI: 10.1016/j.cub.2017.10.002

Adenomatous polyposis coli nucleates actin assembly to drive cell migration and microtubule-induced focal adhesion turnover. Juanes M.A.*, Bouguenina H., Eskin J.A., Jaiswal R., Badache A., Goode B.L. (*co-corresponding author). Journal of Cell Biology, 216(9), pp. 2859–2875. DOI: 10.1083/jcb.201702007

Rot1, an essential yeast protein, is degraded through the ER-associated protein degradation system (ERAD). Juanes M.A.*, Martinez-Garay C., Bañó M.C.* (*co-corresponding authors). PostDoctoral Journal. DOI: 10.14304/SURYA.JPR.V5N11.2

The Mitotic Exit Network. Book chapter. Juanes M.A.* (*corresponding author). Springer, Methods in Molecular Biology. DOI: 10.1007/978-1-4939-6502-1_2

Control of Formin Distribution and Actin Cable Assembly by the E3 Ubiquitin-Ligases Dma1 and Dma2. Juanes M.A., Piatti S. Genetics. DOI: 10.1534/genetics.116.189258

Entangled but finicky ingression protein complexes for successful cytokinesis. Juanes M.A.* (*corresponding author). PostDoctoral Journal. DOI: 10.14304/SURYA.JPR.V4N5.5

The final cut: cell polarity meets cytokinesis at the bud neck in S. cerevisiae. Juanes M.A., Piatti S. Cellular and Molecular Life Sciences. DOI: 10.1007/s00018-016-2220-3

Greatwall kinase oncogenic properties open new horizons for novel human cancer therapies. Juanes M.A.* (*corresponding author). PostDoctoral Journal. DOI: 10.14304/surya.jpr.v4n3.5

A novel role for the RhoA GTPase in the control of septin dynamics for cytokinesis. Merlini L., Bolognesi A., Juanes M.A., Vandermoere F., Courtellemont T., Pascolutti R., Seveno M., Barral Y., Piatti S. Molecular Biology of the Cell. DOI: 10.1091/mbc.E15-06-0366

Transmembrane Ser of Rot1 protein is essential for yeast cell viability. Martínez-Garay C.A., Juanes M.A., Igual J.C., Mingarro I., Bañó M.C. Biochemical Journal. DOI: 10.1042/BJ20131306

Budding yeast Greatwall and Endosulfines control activity and spatial regulation of PP2ACdc55 for timely mitotic progression. Juanes M.A., Khoueiry R., Kupka T., Castro A., Mudrak I., Ogris E., Lorca T., Piatti S. PLOS Genetics. DOI: 10.1371/journal.pgen.1003575

Spindle pole body history intrinsically links pole identity with asymmetric fate in budding yeast. Juanes M.A., Twyman H., Tunnacliffe E., Guo Z., ten Hoopen R., Segal M. Current Biology. DOI: 10.1016/j.cub.2013.05.057

Mechanism for astral microtubule capture by cortical Bud6p priming spindle polarity in S. cerevisiae. ten Hoopen R., Cepeda-Garcia C., Fernandez-Arruti R., Juanes M.A., Delgehyr N., Segal M. Current Biology. DOI: 10.1016/j.cub.2012.04.059

Ase1p phosphorylation by cyclin-dependent kinase promotes correct spindle assembly in S. cerevisiae. Juanes M.A., ten Hoopen R., Segal M. Cell Cycle. DOI: 10.4161/cc.10.12.15864

Actin-mediated delivery of astral microtubules instructs Kar9p asymmetric loading to the bud-ward spindle pole. Cepeda-Garcia C., Delgehyr N., Juanes Ortiz M.A., ten Hoopen R., Zhiteneva A., Segal M. Molecular Biology of the Cell. DOI: 10.1091/mbc.E10-03-0197

Targeting and membrane insertion into the endoplasmic reticulum membrane of S. cerevisiae essential protein Rot1. Juanes M.A., Martínez-Garay C.A., Igual J.C., Bañó M.C. FEMS Yeast Research. DOI: 10.1111/j.1567-1364.2010.00653.x

Membrane topology and post-translational modification of the S. cerevisiae essential protein Rot1. Juanes M.A., Igual J.C., Bañó M.C. Yeast. DOI: 10.1002/yea.1549

Rot1 plays an antagonistic role to Clb2 in actin cytoskeleton dynamics throughout the cell cycle. Juanes M.A., Queralt E., Bañó M.C., Igual J.C. Journal of Cell Science. DOI: 10.1242/jcs.002758