The Juanes Lab is supported by competitive regional, national and international funding. These projects enable us to investigate the molecular mechanisms underlying cell migration, cancer invasion and colorectal cancer, while supporting the training and development of early-career researchers.

New therapeutic approaches for colorectal cancer

CNS2024-154649 — Ministerio de Ciencia, Innovación y Universidades / Agencia Estatal de Investigación (MICIU/AEI)

This two-year project supports the consolidation of the Juanes Lab and the development of new therapeutic approaches for colorectal cancer, with a particular focus on drug discovery.

Targeting actin protrusions

PREP2022-000642 — Ministerio de Ciencia, Innovación y Universidades / Agencia Estatal de Investigación (MICIU/AEI) and FSE+

This four-year predoctoral fellowship supports Irene Olivas Cano’s PhD research at the Juanes Lab. Her work investigates actin-based protrusions and their contribution to cancer cell migration and invasion.

Irene Olivas Cano

FLIP-ACTIN: Flipping the coin — ‘Actin’ for good

PID2022-140899NB-I00 — Ministerio de Ciencia, Innovación y Universidades / Agencia Estatal de Investigación (MICIU/AEI)

FLIP-ACTIN investigates the mechanisms that drive cancer cell migration and invasion, with a particular focus on actin-based protrusions and their relationship with cellular metabolism. The project also supports research personnel and predoctoral training in the lab.

Towards understanding the molecular basis of colorectal cancer in young adults

CIACIF/2022/410 — Generalitat Valenciana

This competitive regional fellowship supports Rabe’ah Almhassneh’s PhD research at the Juanes Lab, focused on advancing our understanding of the molecular mechanisms underlying colorectal cancer in young adults.

Rabe'ah Almhassneh, SEBBM conference

Intramural fellowships

Centro de Investigación Príncipe Felipe (CIPF)

CIPF intramural fellowships support the professional development and specialist training of Juanes Lab members, including external workshops and training placements at institutions such as Institut Curie in Paris and the biotechnology company ProtoQSAR.

Cytoskeletal coordination mediated by APC in collective cell migration

CIDEGENT2021/026 — Generalitat Valenciana

Awarded through the Generalitat Valenciana programme for attracting and returning research talent, this funding enabled Dr María Ángeles Juanes to return to Spain and establish her independent research group at CIPF in 2022.

The project investigates how the tumour suppressor APC coordinates cytoskeletal dynamics during collective cell migration.

CIPF, Valencia

Molecular coordination between cytoskeletal networks in cell migration and its impact on development and disease

SBF006/1070 — The Academy of Medical Sciences (UK)

This Springboard Award supported Dr María Ángeles Juanes in establishing her first independent laboratory at the National Horizons Centre, Teesside University, in 2021. The research investigated the molecular coordination between cytoskeletal networks during cell migration and its implications for development and disease.

Investigation and modelling of cytoskeletal activity in APC-mutated bowel cancer

Teesside University, School of Health and Life Sciences (UK)

This fully funded PhD project investigates and models cytoskeletal activity in APC-mutated bowel cancer. The fellowship supports Lautaro Baro’s doctoral research at the National Horizons Centre, Teesside University.

Lautaro Baro presenting his work

We gratefully acknowledge the organisations that have supported our research, training and scientific development.